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Research on Rectal Ozone Therapy: Mechanism, Safety and Application

Mechanism, Safety Specifications and Applications of Ozone Therapy using the Rectal Route
Clinical Ozone Therapy, as Rectal Ozone Insufflation (ROI), is a Low Invasive treatment and uses the Rectum to receive Ozone infused with Oxygen as a standardised mixture of the two gases Through a Sterile Catheter; This is the Primary non-Intravenous method of administering Ozone Receives through the rectum Mucosa into the body through Capillaries will absorb, Ozone that will enter the body’s systemic circulation and can provide at least three different Biological effects. A Higher degree of oxygen delivered to the tissue, Enhanced utilisation of blood’s oxygen and improvement of microcirculation for blood. The second effect is Modulation of Immune Function and Regulation of inflammatory mediators plus reduction of chronic low grade inflammatory conditions. Two other effects are to Inhibit the Growth of No (Negative effect) Micro organism in the Gastrointestinal (GI) tract and Reduce the Amount of Oxidative stress within the GI tract and Assist in repairing GI Mucosal integrity.

Clinical Application
Ozone Rectum is considered a Safe Alternative (adjunvct) treatment option for multiple chronic pathologic condition often associated with inflammatory bowel disorder such as Ulcerative Colitis and Cohn’s Disease to improve mucosa inflammation of the GI tract and reduce abdominal Distention and Diarrhea, immune modulation of autoimmune sub-health states, improving the ability of the body to chelate toxic materials and support people with chronic constipation and GI Bacterial imbalances and can, also, be used for rehabilitation of systemic chronic inflammatory lesions.

Standard Operating Procedures
There are numerous standardised medical treatment guidelines and procedures that professionals use to correctly administer Ozone therapy as a rectal therapy. The most common guideline is the use of low concentration and quantitatively using the standardised Ozone-Oxygen mixture in an attempt to prevent any oxiditive damage, while conducting Ozone therapy; The administration time for all patients is standardised to 10-20 minutes using disposable and sterile catheters to maintain aseptic technique during the treatments; All patients participating in the treatments are done with a minimum invasiveness associated with no major pain and can be adjuvant treated for a long period of time using multiple therapies under a practitioner’s guidance.

Safety and Contraindications
The use of rectal ozone therapy is considered relatively safe when using the appropriate adult dosages and has minimal risk of any major side effects; some of the relative and absolute contraindications will include: an individual with an active rectal bleedings, risk of perforation of a severe ulcer on the intestinal lining, have acute inflammatory conditions in the abdominal cavity, have a known allergy to Ozone, pregnancy, and coagulopathies. Most adverse effects associated with unregulated high concentrations of Ozone, or too frequent of administration may cause irritation or damage to intestinal mucosal lining, abdominal bloating, or nausea and should be managed by qualified practitioners that have adjusted the treatment to each individual.

Conclusion
As an established Adjuvant method of Ozone Therapy, Ozone Rectum is a highly effective and minimally invasive treatment option for adverse patient outcomes as it applies Ozone to the improving GI microecosystem and the immune system on the Whole Body; therefore, Ozone Rectum provides many therapeutic benefits as an Adjuvant to improve chronically inflamed GI tissue and the sub-optimal resources of the immune system. Therefore, Strict adherence to the Standard Operating Procedures and Individualised protocols is required for the Inherent therapeutic benefit and minimal risk associated with Ozone Therapy.

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