Clinical Summary of Minimally Invasive Ozone Rectal Adjuvant Therapy

Summary of Ozone Rectal Therapy – Popular & Traditional Medicine Overview

1. Ozone Rectal Therapy:
   Ozone Rectal Therapy, a.k.a Ozone Rectal Insufflation Therapy; is a non-surgical adjuvant physical therapy that is safe as well as minimally invasive. An ozone-oxygen gas mixture, prepared under strict medical guidelines, is slowly injected into the rectum using dedicated sterile instruments (e.g., catheter). The gas rapidly passes through the rectal mucosa in order to have both local regenerative effects plus systemically regulate function. It is the one of the most commonly used forms of non-invasive ozone therapy (the other common practice is to inject ozone IV). It is easier to do, more versatile in scope, and much better tolerated by patients than IV ozone therapy.
2. Core Mechanisms of Action:
   Therapeutic activity occurs in both local and systemic ways, with defined mechanisms and without the risk of excessive invasiveness.
   Local Sterilization & Anti-inflammatory Action: Medical-grade ozone is highly oxidizing and actually destroys harmful microorganisms (bacteria, viruses, fungi, etc.) present within the intestines without creating the problem of creating resistance to antibiotics. It also prevents local intestinal inflammation, reduces the amount swelling of the intestinal mucosa (edema), helps heal areas of damage to the intestinal lining and provides an optimal local tissue environment for promoting new cellular growth and maintaining microbial balance (i.e., microbiota) within the intestines.
   Systemic Immunomodulation and Regulation of Metabolic Activity: After being absorbed by the rectal mucosa, ozone stimulates endogenous antioxidant defense pathways as well as increase the body’s total antioxidant capacity. Ozone also helps eliminate excess free radicals and reduces damage resulting from long-term oxidative stress (i.e., chronic oxidative stress).On one hand, ozone rectal therapy has mild, but significant effects on the body. It will moderate the immune system, increase the body’s physical resistance, improve the blood’s oxygen-carrying capacity, increase how the lungs work, and help reduce systemic chronic inflammation.

Three of the main uses of ozone rectal therapy include:

1. Treating intestinal disorders – chronic enteritis, proctitis, recurrent diarrhea, unbalanced intestinal flora, constipation, etc.
2. Treating chronic inflammation – chronic pelvic inflammation, chronic prostatitis, recurrent mild urinary tract inflammation, etc.
3. Improving general physical function – prevent recurrent infections, fatigue from chronic low immunity, or have a difficult time metabolizing or chemical reactions in the body. Patients with a history of not being able to tolerate intravenous (IV) therapy can also use ozone rectal therapy as an adjunct.

To perform this therapy, there are several standardized operating procedures (SOPs) that provide step-by-step guidance:

1. Pre-treatment assessment – medical personnel evaluate the patient’s medical history and confirm the patient’s physical condition prior to commencing treatment.
2. Pre-Treatment Preparation – each patient should make sure that they have completely emptied their bowels and have a comfortable, supine position. The perianal area will need to be cleaned and disinfected very thoroughly just prior to starting the ozone rectal therapy.
3. Ozone Rectal Therapy – using only certified medical ozonated devices, carefully measure out and set the safe concentration of ozonated mixture (O3) and dosages for the patient. Administer and inflate through a special thin rubber tube (prepared prior to the initiation of treatment) slowly and hold the gas inside for several minutes to ensure all of the gas is absorbed through mucosa.
4. Post Treatment Observation – After the patient completes ozone rectal therapy, medical personnel will observe for continued gastrointestinal issues (abdominal distention, dizziness, or other discomfort) for a short period of time (approximately 30 minutes). The patient may resume normal activities immediately if there are no signs of discomfort.

Certain types of patients are excluded from receiving ozone rectal therapy due to the potential safety risk:

1. Pregnant women and acute alcohol intoxicated
2. Individuals with G6PD deficiency (favism), bleeding disorders or individuals with thrombocytopenia
3. Individuals with severe hypotension, profound hypoglycemia, an acute myocardial infarction or individuals who have active abdominal bleeding
4. Individuals with ozone allergy or unhealed acute perianal wounds/infections
5. Key Precautions: Ozone Rectal Therapy can only be performed by credentialed medical personnel and using FDA-approved ozone machines. Patients should not self-administer or attempt to perform ozone colonic irrigation therapy on themselves, as patients operating ozone rectal therapy unsafely believe that if ozone is highly concentrated and/or improperly dosed, the patient may develop mucosal irritation, dizziness or nausea or have other undesirable side effects.

This therapy is an adjunct therapy in addition to physician-prescribed therapies, including, but not limited to, medications or surgery. Patients with organic disorders must still receive care from their physician.

The following physiological sensations and duration of recovery are common after ozone rectal therapy; most patients will have minimal abdominal distention and will relieve themselves spontaneously shortly after treatment. Patients should refrain from eating any cold or hot food for a short time after treatment; increasing the burden on the intestines.

In conclusion, Ozone Rectal Therapy is one type of non-invasive adjunct therapy that is effective for individuals with intestinal inflammatory conditions, chronic pelvic inflammatory disorders and low immunity. In order to maintain maximum benefits from ozone rectal therapy, all ozone rectal therapies performed must be done under strict adherence to the SOP and contraindications, use standard operating procedures, and include ongoing regular sessions for optimal conditioning benefits.